>I'm Laura, CG for my husband of 43 years, Les Rogers, diagnosed with >Parkinsons >in 1995. May I ask those who use Comtan, if you were advised that the >drug would >cause severe hallucinations? SNIPPED Dear Laura-- if it is applicable, I can tell you that Peter , who is at this point very at risk for hallucnations and confusion, is taking Seroquel with pretty good results. (a 25mg tab 4X a day, at least 4 hrs apart). When Comtan was introduced I asked his excellent neuro about it---he chose NOT to give it to Peter because he said it would incrase the hallucinations IN HIS CASE. As you know, all PWPs are unique in their responses to meds. This does suggest, however, that your Les may be at a similar point. Some neuros go for any new drug that comes along, and there are PWPs who do well on Comtan---be aware also that Sinemet and the agonists can be the culprits, and that should also be checked. Peter is now taking only 1mg of Requip, where once he was up to 9mg, and cutting that has helped also. Hallucinations and dementia in general are the pits! Harder to deal with for both parties ,I think, than the physical part of PD. I do hope you can get things stabilized. If he is not seeing a movement disorder specialist, who is very familiar with the variations of PD, please consider at least a consultation with an MDS. Camilla Flintermann, CG for Peter 82/70/55 Oxford, Ohio <[log in to unmask]> on PDWebring at http://members.tripod.lycos.nl/genugten/flinterm.htm "Ask me about the CARE list for Caregivers of Parkinsonians ! " And visit the CARE webring at http://www.crosswinds.net/~caregivers/index.html