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Mr. Charters: Your efforts in putting together all of these websites is most commendable - and useful. It is interesting that the data presented in all of those sites is the data of Dr. Olivier Rascol, professor of pharmacology at the Centre Hospitalier Universitaire, Toulouse, France. He has been working on that data obviously since 1996, when he presented the six month results at the American Academy as "preliminary results." The same data has been presented at the American Academy in 1998 and in 2000, as well as in the International Congress of Neurology. IT IS THE SAME STUDY - only one study. That study has been published and republished and republished - all under the auspices of Smith Kline Beecham. The facts speak for themselves. Jorge Romero, MD ----- Original Message ----- From: "Murray Charters" <[log in to unmask]> To: <[log in to unmask]> Sent: Sunday, June 04, 2000 10:55 AM Subject: Requip Links Was: Re: question for Paul Lauer Hi All, The five-year study of the incidence of dyskinesia in patients with early Parkinson's disease who were treated with ropinirole or levodopa should be viewed in the proper light if you recognize its very narrow focus... "incidence of dyskinesia" and don't try to read anything else into it.... This report was on one aspect only. Here is another narrow focus deliberately taken out of context as a contrast. "CNS adverse experiences were reported by 23% of patients given ReQuip® and by 16% of those who received L-dopa" What does it tell you? (the jury is out, listen to your health professional, don't attempt to self prescribe, don't put too much emphasis on any single study, etc.) Here are some requip / ropinerole links... Requip (Ropinirole) Safely Manages Parkinson's Symptoms Long-term PHILADELPHIA, PA -- May 18, 2000 http://www.pslgroup.com/dg/1d25aa.htm Search Dr. Guide Email Edition for Ropinerole http://www.docguide.com/dg.nsf/searchall/?searchview&query=%5BDocBody%5DCONT AINS(% 22Ropinirole%22)&SearchOrder=1&SearchMax=50&m=exact Search Dr. Guide for SmithKline+Beecham http://www.docguide.com/dg.nsf/searchall/?searchview&query=%5BDocBody%5DCONT AINS(% 22SmithKline+Beecham%22)&SearchOrder=1&SearchMax=50&m=exact The New England Journal of Medicine http://www.nejm.org/content/index.asp http://www.nejm.org/content/2000/0342/0020/1484.asp PubMed http://www.ncbi.nlm.nih.gov/PubMed/ Search on Rascol A five-year study of the incidence of dyskinesia in patients with early Parkinson's disease who were treated with ropinirole or levodopa. 056 Study Group. N Engl J Med. 2000 May 18;342(20):1484-91. (A click on related articles gives you hundreds of abstracts to browse) ReQuip® cuts risk of dyskinesias by 15-fold in early Parkinson's disease http://www.eurekalert.org/releases/medit-rcr071999.html Ropinirole Relieves Symptoms of Early Parkinson's Disease http://www.docguide.com/dg.nsf/PrintPrint/1D585B2EB14DC29F852562FA005C8A2C Parkinson's Disease: New Treatment Options http://www.infomed.org/pharma-kritik-e/abs1719.html Requip (ropinirole hydrochloride, SmithKline Beecham) is an effective treatment for early stage Parkinson's disease http://pharminfo.com/drugpr/requip_pr.html ReQuip More Effective Against Dyskinesia Than L-dopa http://www.pslgroup.com/dg/11a766.htm SmithKline Beecham Parkinson's Disease Press Release - 1/13/98 http://www.druginfonet.com/park2.htm Links to Web sites are provided for information purposes. I assume no responsibility or liability for material on linked sites. Please be advised: Medical information should always be reviewed with your physician or attending professional before attempting to change any medication or therapy. Be forewarned... you must never assume that information obtained from the web is necessarily the best information available (or even valid). Remember, no one sets content rules on the Internet. That said, there is an education awaiting you! Starting here... Surfer Beware http://www.cmdg.org/Surfer_Warning/surfer_warning.htm FDA Consumer Health Information On-Line "Is This Site Reliable?" http://www.fda.gov/fdac/features/596_info.html We can make a difference ......... murray [log in to unmask] View the Parkinson's Awareness Links at: http://www.geocities.com/janet313/pienet/wwweb/index.html