Paul Lauer wrote:
> 3. Protein intake absolutely affects the viability of Sinemet and is a major
> player in the result obtained. In lay terms (and I am a lay person, not a Dr.),
> the Sinemet competes with the medication for carriers into the brain and when
> present, will win, thereby lessening the medication's impact.
Just a tiny correction here. The amino acids obtained from the
proteins are indeed competing with the dopamine, an amino acid too) in the
Sinemet, and the smallest ones will likely reach the active sites first, thereby
crowding out the later ones.
> I have learned from Kathrynne ("Five Star") that daily protein intake should
> approximate 0.8-1.0 grams per kg of body weight. Try to limit your morning meal
> protein and lunch meal protein to perhaps 5-10 grams each and intake the
> balance with dinner.
She is the expert, and that advice sounds good.
> Also try to take your medication at least an hour before eating to give it a
> good headstart into your brain before the protein gets a chance to interfere.
That depends upon the timing of the Sinemet. In a case like ours, my wife has 2
1/2 hr. between Sinemet. Thus, we amble down to dinner after taking the Sinemet,
and she can eat some fruit appetizer, but then we expect to eat soup and entree
about half hour after ingesting the Sinemet. In the residence wherein we live,
we can expect dinner to take about an hour, and then we have another hour before
the next Sinemet.
In fact, it has become even difficult for Barb to eat ice cream after dinner
because the next Sinemet, even an hour later, will lose its effectiveness; so
then I take it to the apartment where she will enjoy that ice cream before
turning in. After 11 years or so after diagnosis, it seems that most fresh dairy
products will adversely effect the therapeutic benefits of Sinemet.
Michel
