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My reply to email from Mr. Page @ Lilly. Question to list: would anybody else like to second my thoughts directly to Mr. Page? -----Original Message----- From: Larry Fleming [mailto:[log in to unmask]] Sent: Wednesday, June 07, 2000 10:16 AM To: [log in to unmask] Subject: Permax Stephen, Thanks for info. I was diagnosed three years ago and I just added Permax (.5mg X 3/day) to my existing selegiline regime. I must say I have noticed a considerable improvement in the quality of life. I do however expect to be eventually priced out of my health insurance coverage. I have an eighty year old friend with PD who was priced out along time ago and had to discontinue her Permax because she could not afford it. When I was younger I worked in a pharmacy and the pharmacy openly advertised an insulin discount with Lilly's support (I believe). Could not Lilly again promote the reduced price sale of Permax to the PWP's who can no longer afford third party coverage and have to pay cash? I think you would find a sales increase because of the increase in scripts that are filled and not thrown away. This would also fend off the production of Pergolide Mesylate by the generic companies. The intangible would be the PR and respect that would be well deserved from the PD community (including national exposure through involvement with Michael J. Fox et al). Do you see any merit to these ideas? Thanking you in advance for your time and consideration. Larry Fleming [log in to unmask] www.bpl-online.com www.flemco.com -----Original Message----- From: [log in to unmask] [mailto:[log in to unmask]] Sent: Wednesday, June 07, 2000 9:04 AM To: [log in to unmask] Cc: [log in to unmask] Subject: Eli Lilly Dear Mr. Fleming, Dr. Gary Tollefson forwarded me your message concerning Permax....I am the Global Marketing Manager for Permax....discovering and developing new effective treatments for Parkinson's Disease is an on-going process for Eli Lilly &Co......Currently all efforts are in their very early stages of development....In addition, we are continually looking for discoveries and opportunities with our many partners in Neuroscience Discovery....I hope that your symptoms are being managed effectively with your current treatments.....Your question about the patent for Permax:, the patent for Permax expired in February of 2000...The manufacturing process for Permax is very expensive and complicated....I am not aware of any generic pergolide available anywhere in the world... I want to thank you for your continued committment and support of Eli Lilly and Co...Best wishes to you in the future....Sincerely, Stepehen L Page