> If there were no Comtan or levodopa a number of amines including > catacholamines such as norepinepherine seratonin and dopamine exist in > theperipheral circulation most of which utilize the COMT pathway. Charlie, does this mean that if one uses comtan, there should be more seratonin, norepinepherine, as well as dopamine circulating and getting through to the brain? Marling 51/5 still trying to laugh