can anyone advise me as to best time to take comtan. jack has been taking it when he gets up about 8am with his sinemet on an empty stomach. then he eats breakfast an hour later. it seems to be helping a little but he gets shaky about 3 pm. i am wondering if it would be better if he took the comtan either with meals or after them. he still wants to wait before calling neurologist.all the perscription says is take in morning. hope you can give me an idea how others take comtan sincerely connie