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Thanks Murrary, You're a genius, leave it to a librarian to expect everything to be written in a book. ************************************************************************* To those who offered to help with a PD quilt, YES, I'll take all the help I can get. Let me think things over a few days and I'll get back to you off line. This is a very busy week for me, so thinking is just about all I can do about the quilt right now. **************************************************************************** There is such a thing as Carbadopa intolerance, I know, because I suffer from it. Its not the Levodopa which causes the problem its the Carbadopa. I put in a whole research paper on the PIENO,I did it several years ago, it has to be in the archives. I don't have time to look for it right now, but Carbadopa does cause Purpura, and I have 2 legs and an arm to prove it!!!! I went off Sinemet for about 9 months, and it all cleared up. I took Laradopa, but I had to eat 3 full meals a day to tolerate it, and I never did get up to full dosage, so my ND and I decided to put up with the Purpura. As Ever, just me, Marjorie 67/12