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Hi Camilla, I tried that, and the shelf life for the 10/100's for me at least was about 2.5 hours. As I said, I'm just not going to be taking medicines every 3 hours. That maybe the wrong attitude, but that is the way I feel. At least when I took Levodopa alone (Laradopa) it did last about 4 hours, but by the end of the day I was really shot, and didn't care to eat a 4 th. meal to tolerate the Laradopa. Carbadopa is the product which extends the life of the Levodopa and makes it cross the brain-blood barrier faster. Levodopa alone WILL cross the brain-blood barrier, it just takes about 3X's more to do so. At least this is what my ND told me. I got up to 750 mg. of Laradopa per day, but some evenings I went to bed early because I was really too fatigued to stay awake any longer. Life is too short, I'll never accomplish what I want to in this lifetime anyway, but sleeping to me is a waste of time. I only sleep when I can't keep my eyes open anymore. Guess I'm afraid I'll miss something!!! just me, Marjorie At 05:20 PM 06/19/2000 -0400, you wrote: >Marjorie-- But if you took 4 of the 10/100 you would get the same amount of >Levodopa, and 40 mg of Carbidopa instead of 100. Why wouldn't that be a >good idea? Peter made that switch long ago, as he takes many more Sinemets >and was getting far more carbidopa than he could utilize. > >Ron wrote: > >have you tried to minimize the amount of carbidopa that you take? use > >only 10/100 tablets? > >just ron > >-- > >Ron Vetter 1936, '84 PD dz > >mailto:[log in to unmask] > >http://www.ridgecrest.ca.us/~rfvetter > > > > > >Hi "just Ron", > > > >I only take (4) 25/100 tablets of Sinemet daily, sometimes > >I forget to take them and only take 3. One before each meal. > > > >I refuse to set my wristwatch timer and become a slave to my PD > >by having to take medication every 2 hours, its just my own > >thing, but I couldn't,nor would I want to live that way. > >I WON'T let it conquer me!!! > > > >So, according to my ND its the total amount I take, and I take > >the least amount possible. > >I don't take anything else, no requip, no miraplex, no eldepryl, > >nada!!! > > I have found out over the years, the least amount of medication > >I take, the better off I am. > >But thanks for your suggestion, and taking the time to answer. > > > >As Ever, > >just me, > >Marjorie > > >Camilla Flintermann, CG for Peter 82/70/55 >Oxford, Ohio > <[log in to unmask]> > > on PDWebring at >http://members.tripod.lycos.nl/genugten/flinterm.htm > > "Ask me about the CARE list for > Caregivers of Parkinsonians ! " > And visit the CARE webring at >http://www.crosswinds.net/~caregivers/index.html