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Ervin McCarthy wrote: >Hi Camilla and Marjorie. There is much discussion about 10/100 & 25/100. I >have recently been prescribed 25/250 Sinemet which seems to be out of the >norm. Would >appreciate discussion on 25/250 Am a little concerned it is too heavy for >starters. > To Ervin and all, I just want to tell all of you I was on Sinemet CR when my colon ruptured in 1996. To this day I blame that medication because it constipated me so badly, and even after 4 years, I'll never take another one!!! Of course constipation can occur naturally I know, but I never had trouble with it until I had been on those pills for 3 months, I was lucky, ~~~ I lived. Intestinal blockage has killed a number of people. As Ever, Marjorie