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As both a PWP and a Physician, I have a dual perspective. For the non-Physician, a journey through the PDR and the seemingly endless lists of POSSIBLE complications is both frightening and intimidating. As a PWP I can only state my personal experience. I have been on Mirapex 1.5 mg three times a day and the experience has been wonderful with no side effects. It has restored my gait problems to the point where I can start to run again albiet it at a minimal distance and a slow shuffle. My sense of well being has been improved. However, it has not helped my visual, dexterity, urinary or thought progression problems. I also attribute a stabilization of the sinemet dose progression to the Mirapex. As a Physician I can only re-emphasize the importance of listening to one's own Physician and reliance on their judgement regarding medications. Predicting in advance the exact "cost-benefit" relationship of any medication is for the average patient about equal to the use of crystal balls or tea leaves. Good Luck, Ken Janis