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Hi Cari, ^^^^^^ WARM GREETINGS FROM ^^^^^^^^^^^^ :-) Ivan Suzman 50/39/36 [log in to unmask] :-) Portland, Maine land of lighthouses 69 degF :-) ******************************************************************** I am in my 15th YEAR of PD, like your dad - so here are a few ideas that I hope may help you---- They are interlaced with excerpts of your original text, below. Ivan Suzman 50/39/36 On Mon, 19 Jun 2000 16:04:33 EDT Cari Barrett <[log in to unmask]> writes: > 1. we are always trying to balance out the dyskinesia with the > Tasmar/Sinemet 25-100 Cari, You can try cutting the Tasmar down to 50 m per dose, but splitting the 100 mg tablets with a pill-cutter. I do--it helps avoid dyskinesia.from the-too-strong 100 mg.he takes now. It's justa hunch I have from having used Sinemet, SInemet CR 25/100 and Tasmar (and Eldepryl) jointly for two years and 4 months. > > 2. he has an extremely hard time (usually) getting up in the > morning, CARI, have you tried giving your dad Sinemet or SInemet CR after 5 PM?? His body will require some dopamine throughout the night. I am pretty sure that this will reduce his morning difficulties. FInd out if your doctor will agree to prescribe at least one or two more doses of Sinemet and Sinemet CR after supper. Looks very much to me like 8 PM and maybe 11PM doses could help your dad tremendously. I take 9:30 PM, after-midnight and 3:45 AM doses. Otherwise. I would be TOTALLY frozen up by morning! > > 3. We are considering the CR 25-100 now that you all told me > exists, but > haven't done it yet - as we realize that 1/2-ing and 1/4-ing the CR > is insane > - but > > if he takes 1/2 CR at 9a for several days - he's totally hyper and > out of > control until the evening - > > if he takes 1/4 CR at 9a for several days (during our "trial > periods") he can > hardly get out of bed at all, has little or no energy and can barely > speak - Loks like he needs more than 1/4 (Dmore than 50 mg), but less that 1/2 (less than 100 mg) If you try to guess, maybe 75 mg per dose would be bettert: 3/4 of a 25/100 CR, each dose. > > anyway - i wish i understood better AND would appreciate a > RE-DIRECTION to > whatever chart that is that helps you figure out the "lifespan" of > the > Sinemets (3 hrs with CR, etc...) > > thanks - > Cari > daughter of Dempsey-PWP (71/16+) > & Jo Ann-CGiver