Dear Nancy, Your symptoms should be addressed promptly by your physician; there are many possible causes, including orthostatic hypotension, low blood sugar and dehydration, or any combination of these and other conditions. The Sinemet package insert states that a few people may experience abnormal blood glucose, either elevated or lowered, so that could be a consideration. I encourage you to ask your physician for a referral to a registered dietitian, preferably one who is experienced in PD, to help you deal with these concerns. My very best regards, Kathrynne Nancy Spires wrote: > > i'm feeling faint. during night i wake up (needing to void), perspiring, > weak, afraid i will pass out. i remove nightwear (w/assist), request > washdown w/wet cloth, ask for juice. take a sinemet and pray i don't fall > off "throne". > i'm not sure if it is need of sinemet, sugar, low bp. > i think it occurs more often when i increase sinemet. i'm now up to 8 > /day--25/100 reg. i'm trying to use more salt. > neuro does find big drop in bp upon standing. i've had lab work done; i > suspect he will advise bp stabilizer. i would prefer not to add more > meds. bp was border high before sinemet. now sitting = av/norm. also sugar > was normal before sinemet. went through diabetes scare so dieted and have > sugar under control (cut out soda and juice). > any advice (i've tried eldepryl, meripex, comtan, amantadine--i seem to get > weaker/worse....no strength, depressed, constipated--go to bed) > diag 95, age 59 now. nancy spires. -- Kathrynne Holden, MS, RD Author: "Eat well, stay well with Parkinson's disease" "Constipation and Parkinson's" -- audiocassette & guidebook "Guidelines for Medical Nutrition Therapy for Parkinson's disease" & Risk Assessment Tools "Risk for malnutrition and bone fracture in Parkinson's disease," J Nutr Elderly. V18:3;1999. http://www.nutritionucanlivewith.com/