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Ivan, I also have some "tipping." Fortunately I tip to the left, which matches my political leaning. I am not experienced enough to completely answer the end of dose question...but with me it seems to me to more associated with a bad day, than the end of a dose. Jim Dolan 58/58/? At 05:39 AM 07/06/2000 -0400, you wrote: > A science question about "TIPPING" sideways in PD: > >(no, I do NOT mean while "tipsy" in a Police Department!!) > > > Does anyone know if striatal dopaminergic nerve cells >that specifically control BALANCE have been identified? > >I have a friend who complains of having balance problems >as many as 12 times a day. She "tips" to the side , >suddenly. She has no tremor , and is not diagnosed with >any movement disorder, including PD. > >I've noticed this "tipping" happens to me when my medicines >are wearing off, especially if I "push it" too hard to finish >something I'm doing, instead of sitting down, relaxing, >and taking my next dose of medicines on time. > >Is this sideways "tipping" at end-of-dose familiar to anyone? > >P.S. Does a drunk's sideways tipping come from >the same origin as a PWP's ?? > >Ivan 50/39/36 >