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Gail Vass said in part: Stress sure makes PD symptoms worse! Hugs, Gail Vass I would definately agree with this statement. It's strange how when vacationing last month with no timetable, no alarm, no deadlines I could go several hours past normal med time with no dire effects. Seemed the lower level of stress caused the meds to last longer. It was great! Now, back at home and with daily stress back to normal, it is necessary to watch the med time more closely than when stress was much less. Now if I could just be on vacation ALL the time<wishful thinking>. Jeanette Fuhr