My father's oncologist just told us that he could not recommend my dad have surgery or even a minimally invasive laporascopic RFA (a new procedure that has just been FDA approved for liver metastases) if he were to need it because he says whenever you put a person with a movement disorder under anesthesia it risks progressing it. Dad is 81 but in very good condition....... I am interested in anyone else who has had this experience of anesthesia worsening movement disorders. As many of you know I am a young-onset pwp (at age 20) just turned 40. Before the age of 20 I had a total of 6 knee operations and since the age of onset I have had 4 other surgeries. A cyst was removed from the back of my right calf three years ago. The procedure was only expected to last 30-45 minutes but due to the cyst being larger than anticipated the surgery lasted 1 1/2 hours. I thought I would never recover from that surgery. My tremors seemed to have worsened at the time. Over the time of recovery the tremors lessened almost as if the brain was recovering from anesthesia. Something else that is interesting is I have a high threshold for drugs meaning it takes a heck of a lot of anything to work as far as relieving any pain. For instance at the dentist what would normally take 1 shot of novacaine takes me 3-4 shots to numb. Even orthopedic pain is extremely hard to treat. It makes it difficult because pain increases symptoms of pd. Plus doctors are reluctant to prescibe anything too high powered because of the pd. So what is a person to do? I have fallen 3 times in the past two weeks from my dyskinesias knocking me off balance. I am using my wheelchair more for fear of the possibilites of broken bones. I have to admit I am not handling this very well. I am hard headed but not dumb. Is it time for DBS because of dyskinesias? Any opinion is welcome. Thanks so much for the shoulder to lean on guys knowing I have my "pd list family" helps. Keep up the fight...we are all in this together. sandy aka sassypwp Sandra Norris "Faith is the daring of the soul to go farther than it can see."