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Tony, Thanks for the reply. So far the evidence for benefit is pretty circumstantial. What I am finding are a lot of references to the same study done back in 1993 and heavily criticised for its subjectivity. Even your links refer to that study. Of late, the only studies I can find on Enada relate to Chronic Fatigue Syndrome. I am using Enada and subjectively I think it is of some benefit, but I'm going to have to devise a controlled trial to work out whether I'm kidding myself. Thanks for your input. -