Mary Ann, Did you reduce the Sinemet when you got a positive reaction from the Comtan? Dyskinetias are caused by too much Sinemet activity. If the Comtan is making the Sinemet more active you need to take less Sinemet. That is what Comtan is supposed to do. But it works for some people and does not work at all for others. Paul ----- Original Message ----- From: Mary Ann Ryan <[log in to unmask]> To: <[log in to unmask]> Sent: Friday, July 07, 2000 6:30 PM Subject: Re: Fw: comtan??? Connie wrote: > I believe they have misinformed neurologists. I believe the > correct dosing for Comtan is to take Comtan with EACH dose of > Sinemet --- unlike Tasmar. Not necessarily. My husband takes only 1 Comtan a day. He has severe dyskinesia and his doctor is being careful not to cause an increase in the problem. ---- God bless Mary Ann (CG Jamie 60/20)