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Carol, we, that is Barbara gets it in technicolor, and it comes with shrieks and agitations. Both Sinemet and Permax may yield side or adverse reactions such as hallucinations, nightmares, and even psychosis. Yet you cannot separate PD from Sinemet for without it, one cannot function. Thus you are between a rock and a hard place, and we have to deal with it as best we can. That's where the use of antipsychotic drugs such as Seroquel comes in. Good luck, Michel Carol Gray wrote: > Does anyone else have this problem? Is it tthe disease or the > medicatiion?? > sinemet 25/100 = 11daily, permax l mg. = 3 daily and tasmar 200 mg = > 3 daily >