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Thursday August 3 5:39 PM ET
Company to Launch Test for Parkinson's in Europe

By Richard Woodman

LONDON (Reuters Health) - The world's first diagnostic
test for Parkinson's disease has won European
marketing approval and will be launched in the autumn,
Nycomed Amersham announced.

The new test, DaTSCAN, is expected to cost around 500
to 600 but should transform the present situation
where up to 25% of patients diagnosed as suffering
from Parkinson's actually have Essential Tremor,
company sources said.

The iodine-labelled agent binds to the dopamine
transporters on the neurons in the brain. The number
of these neurons, and therefore the number of dopamine
transporters, is significantly reduced in Parkinson's
disease.

``There are around 500,000 Parkinson's disease
sufferers across Europe, with 60,000 new cases
diagnosed every year,'' the company said in a news
release. ``DaTSCAN is the world's first diagnostic
agent approved for use in identification of
Parkinson's. Currently the only objective test for
Parkinson's disease is performed post mortem.''

John Padfield, chief executive of the imaging
division, said: ``We have managed to bring a truly
unique product to the market that will satisfy unmet
medical needs and benefit thousands of patients who
may be suffering from Parkinson's Disease.''

A company spokeswoman told Reuters Health that in a
clinical trial involving 250 patients, the results of
the scan were different to the clinical diagnosis in
ten cases. ``In five of those cases, the clinicians
changed their diagnosis. In five further cases, they
decided to continue monitoring the patient.''


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