Abe, it can take at least that long to notice effects from Comtan. However, for a professional opinion, you might e-mail your question to Dr. Abe Lieberman, a leading neurologist specializing in Parkinson's disease. If you'd like to do so, go to the NPF website: http://www.parkinson.org/ scroll down the page and click on Ask Dr. Lieberman, NPF Medical Director Follow the directions, and you'll be able to e-mail Dr. Lieberman directly. He usually responds within 48 hours. My very best regards, Kathrynne Abe Sirota wrote: > > I am taking CAMTAN FOR THE last 2 weeks.no improovement-is somebody has > expiriens with camtan abe sirota aol.com -- Kathrynne Holden, MS, RD Author: "Eat well, stay well with Parkinson's disease" "Constipation and Parkinson's" -- audiocassette & guidebook "Guidelines for Medical Nutrition Therapy for Parkinson's disease" & Risk Assessment Tools "Risk for malnutrition and bone fracture in Parkinson's disease," J Nutr Elderly. V18:3;1999. http://www.nutritionucanlivewith.com/