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On Mon, 14 Aug 2000 14:02:22 EDT, Bonnie Rowley <[log in to unmask]>: >My father has said several times recently that he does not have on/offs - or >at least he cannot tell the difference between the two. My mother, who is >with dad all the time, has commented that there is such a fine line between >the on & off. His main symptom is bradykinesia but he also has tremor. He's >now up to 12 Sinemet a day. >Any comments My wife, Marge 76/65, is presently on minimal dosage of 25/100 three times a day, but has been on higher earlier. I have NEVER seen an on/off condition with her dosages.