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I had the exact same experience as Charlotte and the same result from Baclofen - and a change in the timing of my Sinemet. I now cut the tablets in half and take them every 2 hours instead of 1 whole every 4 hours. It is much smoother for me and also avoids the dyskesias you describe. I also got relief from regular massages and a chiropractor since I had my neck so screwed up from the constant (painful as you say!) twisting. Good luck! Jan (51/47/45)