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I don't know if anyone can help, or knows the answer to this, but I am in quite a bit of pain and hope maybe someone else has had this happen. I worked outdoors today, quite a bit of hand labor involved. About 9am, as I went off meds, my hand cramped up and twisted into my chest - just like normal. However, even after the sinemet kicked in, the back of my hand remained sore. I assumed it was from the exercise, and didn't really worry about it. However, after I got home and cleaned up, I noticed a spot about the size of a dime on the back of the hand. The swelling has continued, and is now closer to the size of a silver dollar, and raised up over 1/2" tall. It is also very painful. Any ideas on cause and/or something to help? Ice and heat are not seeming to help this. Thanks bob aka tex _________________________________________________________________________ Get Your Private, Free E-mail from MSN Hotmail at http://www.hotmail.com. Share information about yourself, create your own public profile at http://profiles.msn.com.