On reading this...I can't help but wonder if this is connected to the "chest pain" that has on occassion sent a few Parkies [including me sister] to the emergency room? My sister thought she was having a heart attack, went to the ER and her heart was checked out as fine. Just makes me wonder. Hugs, Gail Vass ps...to clarify an issue about muscles...the body has 3 types of muscle...cardiac muscle of the heart, smooth muscle of the gut, and striated muscle of the skeletal system...they are not the same. .......... Jackie sent: More on PD and the Heart Parkinson's Affects the Heart Too Parkinson's disease is typically perceived as a brain disorder that causes people to twitch and shake uncontrollably, but new research indicates the heart suffers too. Scientists at the U.S. National Institute of Neurological Disorders and Stroke, a division of the National Institutes of Health, used positron emission topography (PET) to examine the hearts of 29 Parkinson's disease patients. They found that nearly all of the patients had damaged nerve endings around their heart. These nerve endings are responsible for producing a chemical called norepinephrine, which play a role in sending signals between nervous cells.