Margie: You wrote: In fact, he tried Requip for a time and then went back to Mirapex I am curious about this as my husband tried the same thing. He had been on Mirapex for a couple years and thought he would see how he did comparatively on Requip and decide which worked better for him. Within 4 days of taking the Requip instead of Mirapex he regressed back to what he was like before he was diagnosed. It was like his body did not recognize the Requip at all. As he is still working full time, he can't afford to feel like that when the Mirapex was working for him. Within resuming the Mirapex, he felt better the very first day and by the 2nd and 3rd day, he was back to his "normal" self. What kind of experience did your husband have? Juelie, CG for Dan 52 Dx 2+