As Sen. Brownback continues to add one word amendments to the stem cell research bill, in order to block NIH funded stem cell research, it is hopeful to hear that in our global community, private industry and academic institutions are continuing to move the research forward. AAP NEWSFEED September 28, 2000, Thursday SECTION: Nationwide General News; Finance Wire LENGTH: 573 words HEADLINE: BresaGen in $15.3m share placement, for Parkinson's work BODY: BresaGen ASX Codes: BGN MELBOURNE, Sept 28 AAP - Biotech company BresaGen Ltd said today the $15.3 million it had raised through the placement of 10 million shares would be used in its bid to develop a cure for Parkinson's disease. Intersuisse Ltd arranged the private placement of shares at $1.53 each to institutions and professional investors. "The primary purpose of the funds from the placement will be to realise the benefits of the CytoGenesis Inc acquisition," BresaGen said in a statement. BresaGen last month announced it would acquire the US-based company, specialising in stem cell and imaging technology, central to BresaGen's work on Parkinson's. "A core part of BresaGen's intellectual property is stem cell therapy and the acquisition of CytoGenesis will likely advance our stem cell program by about two years," said Dr John Smeaton, managing director of BresaGen. "One of our most important applications for stem cell therapy will be to develop a treatment for Parkinson's Disease." BresaGen announced last month that it is acquiring human stem cells from the University of Wisconsin. These cells will be used at the University of Adelaide for research purposes by Professor Peter Rathjen. "With the expertise of CytoGenesis we are now closer to isolating our own human stem cells and finding a cure for Parkinson's," said Dr Smeaton. "The next step is to establish an animal model of Parkinson's Disease which should lead to clinical testing of human cells." Overseeing this vital next step will be Dr Curt Freed, the leading physician treating Parkinson's Disease with cell therapy approaches in the US. The successful isolation of human stem cells and the development of catheters, software and imaging technology will enable the delivery of cells to Parkinson's patients in a precise and repeatable way. The research would be conducted at a number of North American institutions including Stanford University, University of Georgia, PAGE 2 AAP NEWSFEED September 28, 2000, Thursday University of Minnesota and University of Toronto, where CytoGenesis has research agreements. "The combined companies are positioned to become an industry leader worldwide. The initial goal of treating Parkinson's Disease will necessarily involve techniques for producing new cellular implants and precisely delivering them to the patient. We now have all the skills required," Dr Smeaton said. Cell therapy is the use of healthy cells to replace diseased, non-functional cells. The therapy could change the basis of medicine with direct applications for the treatment of Parkinson's disease, stroke and other neurodegenerative diseases. The incidence of Parkinson's disease is increasing with the aging of the population and current therapies offer no long-term treatment for the disease. The market for an effective new treatment of Parkinson's Disease has been estimated to be over $ US1 billion ($ A1.87 billion) per year. The placement and acquisition of CytoGenesis Inc are subject to shareholder approval at a BresaGen general meeting in Adelaide on November 9. Bresagen shares closed down four cents to $1.56. LANGUAGE: ENGLISH LOAD-DATE: September 28, 2000