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Howdy list Friends, With my participation in a drug study ending in August....I have been titrating up on a dopamine agonist (Mirapex) and I am now at my full dose (.50mg-3x/day).....while I realize that there are many different side-effects in response to the medication and that each individual my experience some, all or none of these......my question is.......do you find that you can experience one side-effect for a while and then suddenly a different side-effect begins???? In my case, for the first month I was very fatigued and was nauseous all the time......these seem to have passed and now I'm experiencing insomnia and headaches. Since I'm relatively new at this, I was wondering if this is common???? Thanks in advance for your responses. Kelly in Calgary 40\39\36