> Hello List Family, I have a friend with Pd that has suffered with
>dyskinesias off and on since 8:00 am. I just got off the phone with
>her. She has had only two non-dyskinetic hours today. Here are her
>stats...She has been diagnosed for 4 years, symptomatic for 1 1/2 to 2
>yrs before dx. She is on Sinemet CR 50/200 . She takes 1/2 tablet to get
>her started in the morning. The only other med she is on is Requip. She
>takes the sinemet morning and early afternoon. But today she has only
>had the morning 1/2 tablet...not sure about how much requip she has
>had..maybe 2 doses..or 3. My question is...Is it recommended to cut a
>CR tablet in half? Would this not effect the time-release capability of
>the CR?
Can requip cause Dyskinesia?
You are right, that would destroy much of the CR function. Actually there
is a 25/100 CR, so no need to cut it....I wonder why neuros don't prescribe
that one instead of saying to cut the larger one. I think Requip or any
agonist adds to the effectiveness of the Sinemet, but as she is taking
such a small dosage apparently, and is only 4 yrs. post-diagnosis, it seems
odd that she would have such extreme med-induced dyskinesia.
> I know that in early-onset and early detection only agonists are used
>in order to maximize the dopamine still being produced by the brain. My
>heart is going out to my friend. I told her I would be posing this to
>the list..Any opinions, suggestions and Rph input would be very much
>appreciated. Sandy Norris 40/28/20
>"Faith is the daring of the soul to go farther than it can see."
i wonder if she has called her neuro? If not, wouldn't that be wise if this
is something unusual? It must be miserable! I hope things settle down for
her very soon..
Camilla Flintermann, CG for Peter 82/70/55
Oxford, Ohio
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