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for what it's worth. has your friend considered using a small dosage of regular sinemet to jump start herself in the a.m.? murph 58/10 On Wed, 11 Oct 2000 23:01:49 -0700 Sandra Norris <[log in to unmask]> writes: > Hello List Family, > > I have a friend with Pd that has suffered with dyskinesias off and > on since 8:00 am. I just got off the phone with her. She has had > only two non-dyskinetic hours today. Here are her stats...She has > been diagnosed for 4 years, symptomatic for 1 1/2 to 2 yrs before > dx. She is on Sinemet CR 50/200 . She takes 1/2 tablet to get her > started in the morning. The only other med she is on is Requip. > She takes the sinemet morning and early afternoon. But today she > has only had the morning 1/2 tablet...not sure about how much requip > she has had..maybe 2 doses..or 3. > > My question is...Is it recommended to cut a CR tablet in half? > Would this not effect the time-release capability of the CR? Can > requip cause Dyskinesia? I know that in early-onset and early > detection only agonists are used in order to maximize the dopamine > still being produced by the brain. My heart is going out to my > friend. I told her I would be posing this to the list..Any > opinions, suggestions and Rph input would be very much appreciated. > > > Sandy Norris 40/28/20 > "Faith is the daring of the soul to go farther than it can see."