 |
 |
One of our list members and his family will be in the Duke University Study of Genetic Links and PD. Okay Joe, Since I have your permission I shall indeed post this interesting information to the list. The items below are a part of 2 emails between Joe Hertz and myself. ><snip> >> >>Marjorie: >> >>I thought you might be interested to know I volunteered to join in the >>Duke study (see below) and convinced my two sisters and two of my three >>brothers to also join in (two in PA, one in FL and one in NM). Doctor >>Burton Scott is my neuro. >>EMBARGOED FOR RELEASE: 5 OCTOBER 2000 AT 10:00 ET US >> >> Contact: Richard Merritt >> [log in to unmask] >> 919-684-4148 >> Duke University Medical Center >> >> Duke researchers find specific genetic link to broad spectrum of >> Parkinson's disease cases >> >> PHILADELPHIA -- Parkinson's disease researchers at Duke University >>Medical Center have demonstrated for >> the first time that alteration of a specific gene on chromosome 6 >>appears to contribute to both the common >> late-onset form of Parkinson's disease, and the rarer, early-onset >>form of the disease. >> >> In 1998, Japanese researchers reported that mutation of this gene, >>which they dubbed "Parkin," was responsible >> for autosomal recessive juvenile parkinsonism, a disorder similar >>to, but considered distinct from, Parkinson's >> disease (PD). Mutations in the Parkin gene were found in a small >>group of Japanese with autosomal recessive >> juvenile parkinsonism. >> >> The Duke researchers, applying the latest genetic sleuthing >>techniques to a much larger and more diverse group of >> families with PD, were able to find a small and previously >>undiscovered mutation on exon 3 of the Parkin gene, >> suggesting there may be a genetic link to the various >>manifestations of the disease. "The findings demonstrate for >> the first time a common genetic basis for the different forms of >>Parkinson's disease, and they suggest that the >> Parkin gene might eventually be a useful diagnostic tool for the >>disease," said Duke genetic epidemiologist William >> Scott, who prepared the results of the Duke team's study for >>presentation Thursday at the annual scientific >> sessions of the American Society for Human Genetics. >> <snip> >>Date: Sun, 15 Oct 2000 22:39:28 -0400 >>From: Joseph Hertz <[log in to unmask]> >>X-Mailer: Mozilla 4.04 [en] (Win95; I) >>To: "Marjorie L. Moorefield" <[log in to unmask]> >>Subject: Re: Genetics >> >>Marjorie: I killed the email. If you wish you may send it to the >>list. My father and my great grandmother also had PD. Joe. just me, Marjorie