----- Oorspronkelijk bericht ----- Van: "Robert A. Fink, M. D." <[log in to unmask]> Aan: <[log in to unmask]> Verzonden: donderdag 26 oktober 2000 23:49 Onderwerp: Re: Drooling drugs >> Botox for drooling? I never heard of it. Botox is good for relief of muscle tightness/spasm, but not for drooling so far as I know. Best, Bob << O'Sullivan JD, Bhatia KP, Lees AJ. Botulinum toxin A as treatment for drooling saliva in PD. Neurology. 2000 Aug 22;55(4):606-7. No abstract available. PMID: 10953215 Pal PK, Calne DB, Calne S, Tsui JK. Neurodegenerative Disorders Centre, UBC Hospital, Vancouver, BC, Canada. Botulinum toxin A as treatment for drooling saliva in PD. Neurology. 2000 Jan 11;54(1):244-7. PMID: 10636161 The authors evaluated intraparotid injections of botulinum toxin A in reducing salivary secretions and drooling in nine patients with PD. There was a marked objective reduction in secretion, and two thirds of the patients had subjective improvement in drooling. No side effects were observed. The authors conclude that botulinum toxin A promises to be a simple and effective treatment for the common problem of drooling saliva in chronic neurologic disease. Jost WH. Treatment of drooling in Parkinson's disease with botulinum toxin. Mov Disord. 1999 Nov;14(6):1057. No abstract available. PMID: 10584695