John, we just viewed this story on the NBC Nightly News......and my husband's reaction was "I should be a prime candidate for PD.....we used rotenone widely on the garden when I was a kid at home". My husband has 3 sisters who also worked in the garden, and handled rotenone. My husband and his 3 sisters are now in their late 50's and early 60's......none show any signs of PD at this time.....nor did his parents/grandparents (now deceased). (and grandma lived to be 98.) Unfortuantely, his wife (me)....the one who did not work in the garden at his home nor even visit gardens.....was symptomatic before the age of 30. Guess there is a lot of genetics to be unraveled to find this link to rotenone, or other things in the environment. This report is probably very significant to the basic neurological researchers.....but not yet ready for a lot of public scrutiny or hopeful patients. Rita Weeks 56/12