Hi Murray, Selegiline can be taken with or without food, as you prefer; it can cause dry mouth, be sure to take it with plenty of water if so. It can also make it difficult to sleep, your doctor has probably advised you take it no later than midday. Mirapex can cause nausea in some people; if so, it may be helpful to take with food. It also can cause dry mouth; take with plenty of water, and sip water frequently to keep the mouth moist if this occurs. Best regards, Kathrynne Murray Kastner wrote: > > Kathrynne, you are probably the best qualified to answer a question for me: > > When is best to take meds, before eating, after or during? I take 5mg > of Seligilene (Eldypryl) twice a day and .5 Mirapex three time a day. > > Thanks for your valued advice... > > ,\\urray > .-. .-. > / \ .-. .-. / \ > / \ / \ .-. .-. / \ / \ > /__Murray_Kastner_____\_____/___\___/___\_ ___ mailto:[log in to unmask] > \ / \ / `-' \ / \ / \ > \ / `-' `-' \ / > `-' `-' -- Kathrynne Holden, MS, RD Author: "Eat well, stay well with Parkinson's disease" "Constipation and Parkinson's" -- audiocassette & guidebook "Guidelines for Medical Nutrition Therapy for Parkinson's disease" & Risk Assessment Tools "Risk for malnutrition and bone fracture in Parkinson's disease," J Nutr Elderly. V18:3;1999. http://www.nutritionucanlivewith.com/