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It's been attempted a few times, but were just overwhelmed with applicants. > ---------- > From: Marjorie L. Moorefield[SMTP:[log in to unmask]] > Sent: Thursday, November 09, 2000 8:55 AM > Subject: Re: News:Murray/Darwin/Greg > > Has there ever been any research proving that women are wrong > in their beliefs?????? > > just me, > Marjorie > > > > > At 09:48 AM 11/09/2000 -0500, you wrote: > >Murray, > >Very interesting. Many women would feel that this research is only > >logical since they have always believed we think and react through our > >genitals anyhow. > > > >Greg > >48/35/35 > >----- Original Message ----- > >From: "Murray Charters" <[log in to unmask]> > >To: <[log in to unmask]> > >Sent: Wednesday, November 08, 2000 11:53 PM > >Subject: News: Sertoli cell transplants > > > > > > > Testicles and transplants > > > Cells from the testes could help the brains of stroke patients recover > > > > > > Transplanting cells from the testes to the brain might one day help > > > patients recover from stroke, say researchers in the US. > > > > > > Sertoli cells isolated from the testes release growth factors that > could > > > protect certain types of neurons in the hours following a stroke, > > > reports Cesar Borlongan from the National Institute on Drug Abuse > > > in Baltimore. > > > > > > The growth factors seem to specifically prevent dopamine-producing > > > neurons from dying, says Borlongan. Last year his group showed that > > > Sertoli cells could protect dopamine-producing cells in animals with > > > Parkinson's disease. > > > > > > Now they believe that Sertoli cell transplants could one day help the > > > five per cent of stroke patients whose damage is limited to the basal > > > ganglia, a region rich in dopamine cells. > > > > > > Sertoli cells are also ignored by the immune system in the same way > > > that sperm are not attacked. This means these cells should be a safe > > > and effective way to limit the damage in these patients, Borlongan > says. > > > Because patients can tolerate a transplant of other people's Sertoli > cells, > > > women could receive transplants too. > > > > > > Chain reaction > > > > > > During a stroke, the loss of the blood supply rapidly kills a core > > group of cells. > > > But in the hours afterwards, the damage becomes worse as dead cells in > the > > > core trigger neighbouring cells to commit suicide. > > > > > > Borlongan mimicked the conditions of a stroke using rat cells in a > > culture dish > > > Experiments showed that Sertoli cells protected dopamine-producing > cells, > > > reducing the number of neurons that committed suicide. > > > > > > Borlongan's colleague Paul Sandberg from the University of South > Florida > > > College of Medicine in Tampa has now just completed the first tests in > > rats. > > > By injecting Sertoli cells into the penumbra region of rat brains > > within a day > > > of a stroke, the rats suffered less severe motor deficits. This > > suggests that > > > many of the vulnerable cells were saved. > > > > > > Borlongan knocked out various growth factors produced by Sertoli cells > and > > > found that the most likely protective substance is a peptide called > > glial-derived > > > neurotrophic factor, or GDNF. > > > > > > The advantage of using Sertoli cells to deliver GDNF is that they can > > keep up > > > production for long periods of time. > > > > > > Correspondence about this story should be directed to > > > [log in to unmask] > > > > > > 1157 GMT, 8 November 2000 > > > Helen Phillips, New Orleans > > > > > > http://www.newscientist.com/dailynews/news.jsp?id=ns9999146 > > > http://www.newscientist.com/dailynews/news.jsp?id=ns9999146 > > > >