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To the list members, I had some disturbing news today from my pwp in Australia. He told me that he has felt lousy for a while. In explanation he said that both of his arms and back are very sore and that the area of his liver feels quite tender. As some may remember, he is in nuclear medicine and does know that this is something to be concerned about. I know that his doctor allows him to self medicate and adjust his meds as he sees fit. He told me that he has been taking sinemet, cogentin, comptan and premax, but I do not know his dosage as he doesnt often discuss this with me. I did learn that he discontinued his usage of comptan last week. My question is this: should he be taking comptan at the same time that he takes permax? I appreciate any information and suggestion or help that anyone can give me. *seattle* audrey friend of pwp aussie John 49/42/38?