Fascinating-it just gets more and more complex, doesn't it? We have so much to learn re: the mysteries of the brain. Carole --- Jemima Harrison <[log in to unmask]> wrote: > > > > i've understood that serotonin shortage is implicated > in both cd and pd > > is that your understanding too? > > > I understand PWP can suffer from up to 40 per cent > depletion in serotonin - > a clear reason for depression. That said, serotonin is > not purely linked to > mood and there is increasing evidence that it plays a > role in movement, too. > There's a team in Manchester, UK, working on - and having > success with - > drugs which inhibit/excite serotonin to treat PD and > dyskinesias. It was > this group that proved that the sub-thalamic > nucleus/globus pallidus pathway > was glutaminergic - which led directly to the > introduction of amantadine, > the first non-dopaminergic drug for PD. > > Jemima __________________________________________________ Do You Yahoo!? Yahoo! Shopping - Thousands of Stores. Millions of Products. http://shopping.yahoo.com/