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I took celexa (10 mg.a day). I had bouts of throwing up, weight lose (i don't need to loose weight), significant increase in movement (I don't need that either). Also, I later learned that people with seizures weren't not included in the sample when testing this particular AD. My headaches got so bad I cried. My tolerance for pain level is pretty high i have been told. These same symptoms of nausea, headaches, and increase tremor that interfers with daily living skillss occurred a few years back when I tried paxil. With celexa I tried since May. I thought the symptoms would subside, but they didn't. I was hoping they would. I heard wellbutrin works well with sinemet. What are ur views about AD and added movement with relationship to sinemet dosages and timing of dosses? nancy m. Jemima Harrison wrote: > > > > > i've understood that serotonin shortage is implicated in both cd and pd > > is that your understanding too? > > I understand PWP can suffer from up to 40 per cent depletion in serotonin - > a clear reason for depression. That said, serotonin is not purely linked to > mood and there is increasing evidence that it plays a role in movement, too. > There's a team in Manchester, UK, working on - and having success with - > drugs which inhibit/excite serotonin to treat PD and dyskinesias. It was > this group that proved that the sub-thalamic nucleus/globus pallidus pathway > was glutaminergic - which led directly to the introduction of amantadine, > the first non-dopaminergic drug for PD. > > Jemima