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"Mario A. Gonzalez" wrote: > IKathelyn, > I take 1/2 of the fast acting SInemet 25/100 - albeit I do not chew it - > around 6:30. > Then I go and have some Cereal with milk. > Then around 7 AM I take: > 25/100 SInemet CR - ELDEPRYL 5MG - Ziac ( BP ) and LIPITOR > 11/2 MG of MIRAPEX. Mario, it is likely that your doctor wants you to take 1/2 of the fast-acting Sinemet first thing, so that you can "get going" as soon as possible. But if you eat or drink something high in protein right afterward (such as milk), the protein will block the Sinemet from being absorbed. It is possible that the milk is causing you to lose the good effect of your 1/2 Sinemet. If your doctor agrees, I would try chewing the Sinemet and drinking a small glass of orange juice or grapefruit juice, then waiting 20-30 minutes to feel it "kick-in" before eating the cereal with milk. It may take a few days before you notice a difference, but it is certainly worth a try. > I have also asked myself if I may not be getting dehydrated in the morning, > you know, after you go to the bathroom. It is very possible that you may be dehydrated, and that would add to some of the problems you are experiencing. Eldepryl can create a need for extra fluids. I would be sure that you are getting two quarts (eight 8-oz glasses) of fluids each day, as juices, milk, water. Keep us posted about how you're feeling -- this is a great group of people with a lot of experience and very willing to help. Best regards, Kathrynne -- Kathrynne Holden, MS, RD Author: "Eat well, stay well with Parkinson's disease" "Constipation and Parkinson's" -- audiocassette & guidebook "Guidelines for Medical Nutrition Therapy for Parkinson's disease" & Risk Assessment Tools "Risk for malnutrition and bone fracture in Parkinson's disease," J Nutr Elderly. V18:3;1999. http://www.nutritionucanlivewith.com/