HEllo PIEN'ers: Nigel Harland wrote a few days ago about Madopar taking only 20 min to kick in in the morning: Nigel says:"Although I take Madopar Dispersible ( as opposed to sinemet ) I have found that it is much better to wait until "kick in" has happened, in my case about 20 minutes, before eating or drinking anything, otherwise the uptake of the Madopar can be seriously slowed down." Best Wishes Nigel Harland Sinemet takes 35to 45 minutes to kick in , in me. Multiply 40 min or so by 7 doses per day, and you can see I wait s much as280 min per day, or 4 HOURS AND 40 MINUTES. SO, how do we Americans get Madopar to try? Or are we doomed to 2nd-class status? Do the drug companies have a geographically-organized cartel?? Can that be broken?? Thanks, Ivan Suzman