My husband's answer to Sharon's question about Remeron & back pain is as follows: I had lower back problems many years before taking Remeron. I don't think Remeron made them any worse. I have been taking Remeron for 13 months now. I know studies are going on to better understand it. For more information, you might contact: Dr. Pact Chapel Hill Neurology 101 Conner Drive, Suite 200 Chapel Hill, NC 27514 e-mail [log in to unmask] Any new information you get would be appreciated. I have tried missing a dose of Remeron for one day and tremors return. I wrote an article in the "Parkinsonian People" newspaper, March 2000 issue, explaining my feelings about Remeron. Ed McCaffrey 72/dx1991 In answer to Nancy M.'s question, Ed does not have a problem with orthostatic hypotension or pulse. Nancy McCaffrey CG for Ed