Hi Fran-- Peter took Mirapex for only a few weeks and then switched to Requip because of a very scary paranoid episode due to too much dopamine---his then - neuro wouldn't reduce the Sinemet at once, when starting the agonist ,and he got an overdose. He does not drive, so did not have the sudden sleep attacks that some have had while driving--can be dangerous. I agree with those who have suggested discussing this AGAIN with the neuro, and maybe if you need an agonist one of the others will be better for you--as you know, PD is definitely a matter of "different strokes for different folks" ! Remember too that it may take some time for your body to adjust to a new med, so some side effects may diminish with time. >The Mirapax has tremendous and immediate side effects for me. I feel very >weak and sick. I tried going without it for a day and felt awake and >alert..but for me the tremors returned especially at night. >I have been trying to decide what to do and I am holding off making that >decision until my next visit with my neuro. >When you stopped taking the Mirapex did you have any symptoms return? >Fran Camilla Flintermann, CG for Peter 82/70/55 Oxford, Ohio <[log in to unmask]> on the web at http://members.tripod.lycos.nl/genugten/flinterm.htm and also at http://www.geocities.com/camillahf/index.html "Ask me about the CARE list for Caregivers of Parkinsonians ! " And visit the CARE webring at http://www.crosswinds.net/~caregivers/index.html