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Fran, I would speak with your neuro before going off Mirapex. I have been on it a year and a half, and of all the meds I take, mirapex, sinemet, sinemet cr antiinflamitories and pain meds, the mirapex is the LAST one I would mess with on my own. Those little pills are powerful, and for me at least, do a lot of good. bob aka tex