Carol-- weakness and fatigue are very much a part of PD for many PWPs. The big weight loss may also play a part. This sounds somewhat complicated, and I would hesitate to make specific suggestions, but wonder if you have raised these questions with her doctor? Does she see a Movement Disorder specialist who understands the variations and complications of PD as a general neurologist may not? If you have had no help, perhaps you need a consultation with a MDS---or a new neuro. This sounds fairly extreme for someone only diagnosed a couple of years ago. There are syndromes called PD Plus which are somewhat different from "regular" PD, develop more rapidly and do not respond well to PD meds. It may be important to be sure she doesn't have one of these, and they can be tricky to diagnose. You didn't say how old she is or what meds she takes. This isn't giving you any answers, but some questions to consider--- Have you thought about joining the CARE list for caregivers of PWPs? I just posted about it--let me know if you are interested. >Can anyone help? My mom was diagnosed with Parkinson's a couple of years >ago. Since the summer of 1998 she has lost 45 pounds, and suffers from >debilitating weakness between about 10 am and 2 pm every day. If she lies >perfectly still on the couch, she suffers no tremors, but if she even reads >the paper, she shakes. >Help with information please. >Carol >_________________________________________________________________________ >Get Your Private, Free E-mail from MSN Hotmail at http://www.hotmail.com. Camilla Flintermann, CG for Peter 82/70/55 Oxford, Ohio <[log in to unmask]> on the web at http://members.tripod.lycos.nl/genugten/flinterm.htm and also at http://www.geocities.com/camillahf/index.html "Ask me about the CARE list for Caregivers of Parkinsonians ! " And visit the CARE webring at http://www.crosswinds.net/~caregivers/index.html