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Hi Jane and Hi Kathrynne,

Clonodine appears to be:
Brand Name: CATAPRES
Generic Name:   CLONIDINE HCL (ORAL)
Drug Class: HYPOTENSIVE AGENTS

I read the following Monograph and noted there is mention of what to
do if you also take levodopa (Dopar, Larodopa, Sinemet);

DESCRIPTION:
CLONIDINE HYDROCHLORIDE TABLETS, USP
Clonidine Hydrochloride is a centrally acting alpha-agonist hypotensive
agent available as tablets for oral administration in three dosage
strengths:  0.1 mg, 0.2 mg, and 0.3 mg. The 0.1 mg tablet is equivalent to
0.087 mg of the free base. The following inactive ingredients are
contained in these products: corn starch, hydrous lactose, magnesium
stearate, sodium starch glycolate, D& C yellow #10 Aluminum Lake,
FD& C yellow #6 Aluminum Lake (Sunset Yellow Lake).
Clonidine hydrochloride is an imidazoline derivative and exists as a
mesomeric compound. The chemical name is
2-(2,6-dichlorophenylamino)-2-imidazoline hydrochloride.
Clonidine hydrochloride is an odorless, bitter, white, crystalline
substance soluble in water and alcohol.

clonidine - Pronunciation: KLOE ni deen
Brand: Catapres
What is the most important information I should know about clonidine?
•
Do not stop taking clonidine suddenly. This could cause severely high
blood pressure, nervousness, and anxiety.
•
Use caution when driving, operating machinery, or performing other
hazardous activities. Clonidine may cause dizziness or drowsiness.
If you experience dizziness or drowsiness, avoid these activities.
•
Use caution when rising from a sitting or lying position, especially
first thing in the morning. You may become dizzy while taking clonidine
and you may fall and injure yourself if you get up quickly.
•
Do not use alcohol, antihistamines, prescription pain relievers, sleeping pills,
and other drugs that may cause drowsiness or dizziness except under the
supervision of your doctor.

What is clonidine?
•
Clonidine lowers blood pressure by decreasing the levels of certain chemicals
in your blood. This allows your blood vessels (veins and arteries) to relax
(widen) and your heart to beat more slowly and easily.
•
Clonidine is used to treat hypertension (high blood pressure).
•
Clonidine may also be used for purposes other than those listed in this
medication guide.

Who should not take clonidine?
•
Before taking this medication, tell your doctor if you have any type of heart
disease, have had a heart attack or a stroke, have liver disease, or have
kidney disease.
•
You may need a lower dose or special monitoring during treatment with
clonidine if you have any of the conditions listed above.
•
Clonidine is in the FDA pregnancy category C. This means that it is not
known whether clonidine will harm an unborn baby. Do not take this
medication without first talking to your doctor if you are pregnant.
•
Clonidine passes into breast milk. It is not known whether clonidine will
harm a nursing infant. Do not take clonidine without first talking to your
doctor if you are breast-feeding a baby.
•
If you are over 60 years of age, you may be more likely to experience side
effects from clonidine therapy. You may require a lower dose.

How should I take clonidine?
•
Take clonidine exactly as directed by your doctor. If you do not understand
these directions, ask your pharmacist, nurse, or doctor to explain them to you.
•
Take each tablet with a full glass of water.
•
Take clonidine at bedtime unless otherwise directed by your doctor.
Clonidine may make you drowsy and may cause some dizziness.
Taking it at bedtime may prevent falls and injuries.
•
Do not stop taking this medication suddenly even if you feel better.
You may need to take clonidine for the rest of your life to control your condition.
•
Store this medication at room temperature away from moisture and heat.

What happens if I miss a dose?
•
Take the missed dose as soon as you remember. However, if it is almost
time for your next dose, skip the dose you missed and take only your next
regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?
•
Seek emergency medical attention.
•
Symptoms of a clonidine overdose include drowsiness, lethargy, weakness,
lightheadedness, a slow heart rate, nausea, vomiting, and possibly seizures.

What should I avoid while taking clonidine?
•
Use caution when driving, operating machinery, or performing other
hazardous activities. Clonidine may cause dizziness or drowsiness.
If you experience dizziness or drowsiness, avoid these activities.
•
Use caution when rising from a sitting or lying position, especially first
thing in the morning. You may become dizzy while taking clonidine and
you may fall and injure yourself if you get up quickly.
•
Avoid alcohol while taking clonidine. It may increase the drowsiness and
may also increase dizziness. Use caution even with small amounts of alcohol.
•
Avoid other drugs such as sleeping pills, antihistamines, prescription pain
relievers, and antidepressants unless they are approved by your doctor.
These medicines will increase the drowsiness caused by clonidine.
Talk to your doctor or pharmacist about any other prescription or
over-the-counter medications you are taking.

What are the possible side effects of clonidine?
•
If you experience any of the following serious side effects, stop taking
clonidine and seek emergency medical attention:
 an allergic reaction (difficulty breathing; closing of your throat;
swelling of your lips, tongue, or face; or hives);
·
a very slow heart rate (fewer than 60 beats per minute); or
·
unusually high or low blood pressure (severe headache, redness of the face,
neck, and chest, dizziness, and fainting).
•
Other, less serious side effects may be more likely to occur.
Continue to take clonidine and talk to your doctor if you experience any
of the following:
·
unusual fatigue, dizziness, or tiredness;
·
headache;
·
constipation, nausea, vomiting, or diarrhea;
·
insomnia; or
·
a dry mouth (sucking on ice chips or sugarless hard candy may relieve
this side effect).
•
Side effects other than those listed here may also occur. Talk to your doctor
about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect clonidine?
•
Clonidine may increase the effects of other drugs that cause drowsiness,
including antidepressants, alcohol, antihistamines, sedatives (used to treat
insomnia), pain relievers, anxiety medicines, and muscle relaxants.
Tell your doctor about all medicines that you are taking, and do not take
any medicine unless your doctor approves.
•
Before taking clonidine, tell your doctor if you are taking any of the
following medicines:
·
a beta-blocker such as atenolol (Tenormin), acebutolol (Sectral),
propranolol (Inderal), metoprolol (Lopressor), carvedilol (Coreg),
carteolol (Cartrol), labetalol (Normodyne, Trandate), or nadolol (Corgard);
·
levodopa (Dopar, Larodopa, Sinemet);
·
prazosin (Minipress); or
·
verapamil (Verelan, Calan, Isoptin, Covera-HS); or
·
a tricyclic antidepressant such as amitriptyline (Elavil, Endep),
imipramine (Tofranil), nortriptyline (Pamelor, doxepin (Sinequan), and others.
•
You may require special monitoring or a dose adjustment if you are taking
any of the medicines listed above.
•
Drugs other than those listed here may also interact with clonidine or affect
your condition. Talk to your doctor and pharmacist before taking any
prescription or over-the-counter medicines.

Where can I get more information?
•
Your pharmacist has additional information about clonidine written for
health professionals that you may read.
Remember, keep this and all other medicines out of the reach of children,
never share your medicines with others, and use this medication only for
the indication prescribed.

http://www.subscriberx.com/.SRX?Service=SRXLeaflet&Function=GetLeaflet&DrugId=853&Dialect=English

All the best .......... murray

On 29 Jan 2001, at 18:49, Kathrynne Holden, MS, RD wrote:
>
> Jane, are you sure of the spelling? Clonidine is an antihypertensive
> agent.
>
> Best,
> Kathrynne
>
> Jane Ross wrote:
> >
> > Can anyone tell me what clonodine is used for? My mother is taking it
> > when her blood pressure goes over 200.
> >
> > jjjane
>
> --
> Kathrynne Holden, MS, RD
>

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