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Daily Yomiuri On-Line - Japan
Gynecological society plans to review guidelines on ova
Yomiuri Shimbun
The Society of Obstetrics and Gynecology will review its guidelines on
the use of fertilized eggs produced for infertility treatments to allow such
eggs to be used for research into embryonic stem (ES) cells, a source
close to the society said Saturday.

The review will apply to fertilized eggs not used in infertility treatments,
the source said.

Based on the belief that it is necessary to handle fertilized eggs
carefully because they are the first stage of life, the society has
so far limited use of such eggs in infertility-treatment research.

However, as the government is expected to begin promoting
research into ES cells, the society has identified the need for
a system to secure fertilized eggs for future research on the
cells, the source said.

The society, comprised of doctors, reportedly will compile a
draft to revise the guidelines as early as March, with the aim
of approving them at its general meeting in May.

Cells harvested from cultivated fertilized eggs are used to breed
ES cells.

ES cells can then be cultivated into various types of human cells,
including internal-organ and nerve-tissue cells. Therefore, experts
believe they eventually will be able to use the cells to regenerate
organs inside the body and to manufacture organs for transplants.

The government is expected to establish new guidelines on basic
scientific research in summer, fueling hopes that it will permit
research on ES cells.

However, many patients are reluctant to allow eggs they donate
to be used for research purposes. For this reason, in a 1985 report
expressing its view on research involving human sperm, ova and
fertilized eggs, the society said fertilized eggs should only be used
to develop reproductive drugs and to help improve infertility
treatments.

Based on the guideline review, doctors at a research institute for
cultivating ES cells will brief married couples on ES cell research
utilizing fertilized eggs once they have gained the approval of an
ethics committee of a related hospital. The institute will then be
able to receive fertilized eggs from the couples, provided that they
fully understand the research program.

The planned guidelines reportedly will target patients whose
treatments aim to produce about 10 fertilized eggs at a time to
freeze for later use in vitro fertilization.

Copyright 2001 The Yomiuri Shimbun

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