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Dave- how is the Sinemet 25/100 and sinemet 25/100 CR different?  I know the
latter stays in your system longer but how does it work and why would they
use the Cr instead?

I was switched today from sinemet 25/100 to the 25/100 CR  do they react or
should i expect anything different?    Thanks                     Diane
----- Original Message -----
From: dpurdy <[log in to unmask]>
To: <[log in to unmask]>
Sent: Tuesday, February 27, 2001 6:19 AM
Subject: Re: ?Too much Sinemet


> Mary,
> The 10/100 has the same amt of levodopa. The carbidopa is less. The
carbidopa is
> being used to help the levodopa from being destroyed by enzymes and also
to help
> prevent nausea. It is felt that about 75mg per day is recommended. Excess
> levodopa would probably result in dyskinesia (abnormal body movements such
as
> twisting etc.) You might want to discuss with the doctor that you want to
> experiment with the  dosage a little. Perhaps splitting your levodopa in
half and
> taking it a little closer together might be a wise suggestion. Please let
me know
> your thoughts.
>
> Dave Purdy, retired R.Ph. & Parkinsonian
>
> Mary Legan wrote:
>
> > Please would you answer fast?  What are the signs & symptoms of too much
> > Sinemet?  I've got to get my neuro to put me back to 10/100.  She has
now put
> > me on 25/100.  With new psychiatric meds, too, I need someone to help me
> > Identify the signs & symptoms of too much sinemet so I can at least get
her
> > to go back to what I know was better for me.  She has many gatekeepers,
& I
> > will just be told to stay on what she said.  The thing is, because I had
so
> > many left,  I stayed on it way past when she knew about it.  I just
started
> > the 25/100 about 3 weeks ago, and am so uncomfortable.  Please tell me
the
> > signs & symptoms so I can articulate quickly what is happening.  Would
you
> > send this quickly, if possible?
> >
> > MDawn30475805