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Listmembers Maybe we'tt don't have to wait for Stem cells to get rid of our fear for sinemet. I found two articles today: one on http://www.sciencedaily.com/releases/1998/10/9810160775643.htm. Title: Newly found target in brain may lead to novel Parkinson's disease therapies QUOTE In a normal brain, neurons release a common neurotransmitter called glutamate. It is abundant throughout the brain, playing a role in communication between the various types of neurons. Without glutamate, the brain would seize up and cease te function. Researchers have determined over the apst few years that for Parkinson's patients, insufficient levels of dopamine induce one tiny group of cells in the basal ganglia, called the subthalamic nucleus, to dramatically increase their activity. This hyperactivity means they produce extra glutamate---so much that it overloads the glutamate receptors. Scientists believe that this extra glutamate causes the movement problems in Parkinnson's >>>>>>>>>>>> >>>>>>>>>. "So theoretically, a drug that blocks the activity of glutamate released from neurons in the subthalamic nucleus should have the same beneficial effects as surgery. The other Article http://www.sciencedaily.com/releases/2000/04/000426081102.htm Title; Promising New Parkinson's treatment proves safe QUOTE Remacemide hydrochloride interferes with glutamate activitty and has improved symptoms in animal models of Parkinson's disease. The drug has also been used in clinical trials for epilepsy, acute stroke, Huntington's disease, Parkinson's disease, a chronic neurolgic disease that impairs mobility, is caused, in part, by a progressive loss of dopamine producing brain cells. >>>>>>>> >>>>>>>>>>>.. Theh study was performed by the Parkinson Study Group at21 medical centars nationwide, in a collaborative effort to gather and analyze Parkiiinsons data, and was supported by Astra Pharmaceuticals. Ida Kind regards / Vriendelijke groeten Ida Kamphuis