Sami: I replied to Mario but for some reason it went directly to him and not through the list. Yes, Requip made me sleepy but not to an extent I couldn't handle, even while driving. However, my experience doesn't necessarily presage yours. You will either get sleepy or not and handle it or not. I substituted 9 mg (3 mg 3x/day) for one Sinemet CR 25/100 and one CR 50/200. Apparently the controlled release formulations are somewhat different from the regular. I don't regret it for one minute. Since it eliminated my lunchtime vicinity Sinemet completely, it opened a whole world of protein filled lunches (think Sushi) for me again. Paul H. Lauer ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn