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Chris van der Linden, M.D. wrote:
>
> Apomorphine is used for many years in many countries in Europe. The drug is
> available and not experimental in Europe.
> It is being used for two reasons:
> 1. by some neurologists it is used as a diagnostic tool.  A positive
> response of the drug on the symptoms of PD is in favor of the diagnosis of
> idiopathic Parkinso'n's disease.
> 2. In later stage disease it is used to acutely treat freezing episodes.

Hi Chris- longtime no see! Add this about apomorphine: First used as
powerful emetic (for small kids who have swallowed poison) so it can't
be taken by mouth. Several other methods of chronic delivery as PD
therapy have been tried, the latest was intravenous via implanted
catheter and pump,  but that's no good either, it caused serious
problems requiring cardiothoracic surgery on some. Any who wish to
learn more in a hurry can find about two dozen brief entries in
past Current Science Reviews. Cheers,
Joe
-
J. R. Bruman (818) 789-3694
3527 Cody Road
Sherman Oaks, CA 91403-5013

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