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Dear Group, My GP and Neuro have confered and believe it's necessary for me to take Sinemet, init 1 x 62.5 twice/day, in addition to Pergolide 1mg three times/day. I v.much want to improve my mobility but am concerned of the potential adverse side effects, having read the text on Sinemet at www.dupont.com I would like to hear from any member with the same or similar med therapy, or experience with Sinemet, good and bad. I aim to start on April 1st. regards, Marco ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn